Unique hepatic-derived surgical matrix primed for cellular integration

MiroFlex™ (formerly known as MiroMesh) is a non-crosslinked acellular surgical matrix, derived from the highly vascularized porcine liver. It is intended for implantation to reinforce soft tissue where weakness exists in patients requiring soft tissue repair such as hernia repairs or reinforcement in plastic and reconstructive surgery. If larger sizes of MiroFlex are desired, pieces may be quilted together.

Histologic evaluation of MiroFlex biologic matrix revealed enhanced recellularization with evidence of long-term remodeling and tissue alignment, supporting the mechanical data.

Request more information or a demo here.

An in vivo analysis of MiroFlex (formerly known as MiroMesh) – a novel porcine liver prosthetic created by perfusion decellularization Clayton C. Petro, MD Journal of Surgical Research  2016;201:29-37 Read Here
A comparative analysis of ventral hernia repair with a porcine hepatic-derived matrix and porcine dermal matrix Job Tharappel International Journal of Abdominal Wall and Hernia Surgery 2019;2(3):89-95 Read Here
A multi-center, prospective clinical trial of a hepatic derived porcine surgical mesh for the laparoscopic repair of symptomatic paraesophageal hernias Michael J. Rosen The American Journal of Surgery 2019;218(2):315-322 Read Here
Retrospective review and prospective follow-up of 85 consecutive patients treated with a novel hepatic-derived surgical mesh for hiatal hernia repair: outcomes, surgical complications, and revisions George K. Gillian, MD Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 2019;29(6):529-533 Read Here


Reducing Failure Rates in Hiatal and Paraesophageal Hernia Repair – the ‘Achilles Heel’ of Anti-reflux Surgery Dr. G. Kevin Gillian Florida Chapter,
American College of Surgeons
Watch Here


BLM-100-01-0608 6cm x 8cm 48
BLM-100-01-0808 8cm x 8cm 64
BLM-100-01-1010 10cm x 10cm 100
BLM-100-01-0816 8cm x 16cm 128
BLM-100-01-1016 10cm x 16cm 160
BLM-100-01-1020 10cm x 20cm 200

MiroFlex is processed and stored in a phosphate buffered aqueous solution, packaged in an inner sterile pouch and outer non-sterile pouch, and sterilized with electron beam irradiation. MiroFlex comes in a variety of sizes and is intended for use only by trained medical professionals who are familiar with surgical procedures and techniques involving a surgical matrix. Federal (U.S.A) law restricts this product to sale by or on the order of a physician.

MiroMesh is now MiroFlex. MiroFlex Biologic Matrix is intended to be implanted to reinforce soft tissue and is also intended for implantation to reinforce soft tissue where weakness exists in patients requiring soft tissue repair or reinforcement in plastic and reconstructive surgery.

See IFU for full prescribing information, including indications, contraindications, precautions, and potential complications.

To request a copy of the complete product instructions for use, please email info@reprisebio.com.

A vessel on the open edge of MiroFlex was cannulated and a red dye was injected into the graft to demonstrate the presence of the native liver vasculature, including the capillaries.

MiroFlex is clinically proven for hiatal and paraesophageal hernia repair

  • Unique hepatic-derived surgical matrix with natural vascular pathways
  • Native vasculature is preserved down the the capillary beds (250 µM)
  • Open vascular pathways assist in facilitating cellular integration and remodeling in surgical use

Designed for surgical success


GSA Advantage

Our Technology

Our proprietary process removes cellular material from complex, highly vascularized organs, such as the liver. The result is an architecturally intact collagen scaffold with pre-existing vascular pathways.

Product Inquiries and Orders

Call us at: 763-284-6780

Fax us at: 952-856-5085

Product Inquiries at: customerservice@l5s.bad.myftpupload.com

SM-00154 Rev. E 08/22