Perfusion decellularized hepatic wound matrix primed for cellular integration

Designed for the management of advanced wounds

  • Our proprietary perfusion decellularization process results in an open collagen matrix with natural vascular pathways to assist in cellular infiltration and integration
  • Offered in different sizes to meet the individual patient’s clinical needs

Broad range of clinical uses

MiroDerm is a non-crosslinked acellular wound matrix derived from highly vascularized porcine liver. It is intended for the management of wounds, including partial and full-thickness wounds; pressure ulcers; chronic vascular ulcers; diabetic ulcers; tunneled, undermined wounds; trauma wounds; drainage wounds; and surgical wounds.

A large necrotizing infection in the perivulvar/perirectal space was debrided to the coccyx. The post-op wound was 15L x 8W x 9D cm. Wound V.A.C. was applied. The wound was re-debrided and irrigated, and negative pressure suction device (NPSD) was applied several times over the next three weeks, prior to the first MiroDerm Fenestrated application

Clinically proven to close hard-to-heal DFUs that had previously failed other advanced therapies1

  • Single arm, multi center (9), prospective study
  • All patients were non-responsive to at least two applications of one or more advanced biologic wound care product and wounds had not healed within the previous three months
  • 53 patients enrolled and 38 completed per protocol over 12 weeks

In this study, MiroDerm closed DFUs that had previously failed other advanced therapies. These favorable results are consistent with a similar pilot study.2

Clinical Data

STUDY AUTHOR PUBLICATION FULL ARTICLE
Treatment of Hard-to-heal Diabetic Foot Ulcers With a Hepatic-derived Wound Matrix Robert Fridman, Payam Rafat, Carl C Van Gils, Deena Horn, Dean Vayser, C Jake Lambert, Jr Wounds Epub 2020 June 21

Read Here
A Pilot Study to Evaluate the Effects of Perfusion-decellularized Porcine Hepatic-derived Wound Matrix on Difficult-to-heal Diabetic Foot Ulcers Robert Fridman and Jonathan Engelhardt WOUNDS, October 2017

Read Here

 

STUDY FULL ARTICLE
Treatment of Hard-to-heal Diabetic Foot Ulcers With a Hepatic-derived Wound Matrix Read Here
A Pilot Study to Evaluate the Effects of Perfusion-decellularized Porcine Hepatic-derived Wound Matrix on Difficult-to-heal Diabetic Foot Ulcers Read Here

 

Ordering Information

ITEM ID SIZE TOTAL cm2  GTIN ID
MiroDerm Fenestrated      
BLM-200-02-0815 8 x 15 cm 120 00857072005156
BLM-200-02-0710 7 x 10 cm 70 00857072005149
BLM-200-02-0808 8 x 8 cm 64 00857072005132
BLM-200-02-0505 5 x 5 cm 25 00857072005125
BLM-200-02-0307 3 x 7 cm 21 00857072005118
BLM-200-02-0404 4 x 4 cm 16 00857072005170
BLM-200-02-0303 3 x 3 cm 9 00857072005163
BLM-200-02-0203 2 x 3 cm 6 00857072005293
BLM-200-02-0202 2 x 2 cm 4 00857072005309
MiroDerm Fenestrated Plus      
BLM-200-03-0815 8 x 15 cm 120 00857072005262
BLM-200-03-0808 8 x 8 cm 64 00857072005248
BLM-200-03-0505 5 x 5 cm 25 00857072005231
BLM-200-03-0303 3 x 3 cm 9 00857072005200

MiroDerm Fenestrated and MiroDerm Fenestrated Plus are processed and stored in a phosphate buffered aqueous solution, packaged in an inner sterile pouch and outer non-sterile pouch, and sterilized with electron beam irradiation. The product comes in a variety of sizes and is intended for use only by trained medical professionals who are familiar with wound procedures and techniques involving the use of a wound matrix. Federal (U.S.A.) law restricts this product to sale by or on the order of a physician.

GSA Advantage

 

 

 

MiroDerm Biologic Wound Matrix (Fenestrated and Fenestrated Plus) is indicated for the management of wounds, including: partial and full-thickness wounds; pressure ulcers; venous ulcers; chronic vascular ulcers; diabetic ulcers; tunneled, undermined wounds; trauma-wounds (abrasion lacerations, second-degree burns, skin tears); drainage wounds; and surgical wounds (donor sites/grafts, post-Mohs surgery, post-laser surgery, podiatric wound dehiscence).

See IFU for full prescribing information, including indications, contraindications, precautions, potential complications, and recommended application instructions.

Download IFU here.

References:

  1. Fridman, R; et al. Treatment of Hard-to-heal Diabetic Foot Ulcers With a Hepatic-derived Wound Matrix. Wounds. 2020.
  2. Fridman, R; Engelhardt, J. A pilot study to evaluate the effects of perfusion-decellularized porcine hepatic-derived wound matrix on difficult-to-heal diabetic foot ulcers. Wounds. 2017. Vol. 29, No. 10. pp. 318-32.

Product Inquiries and Orders

Call us at: 763-284-6780

Fax us at: 952-856-5085

Product inquiries at: customerservice@reprisebio.com

SM-00155 Rev. H 05/24