Perfusion decellularized hepatic wound matrix primed for cellular integration
Designed for the management of advanced wounds
- Our proprietary perfusion decellularization process results in an open collagen matrix with natural vascular pathways to assist in cellular infiltration and integration
- Offered in different sizes to meet the individual patient’s clinical needs
Broad range of clinical uses
MiroDerm is a non-crosslinked acellular wound matrix derived from highly vascularized porcine liver. It is intended for the management of wounds, including partial and full-thickness wounds; pressure ulcers; chronic vascular ulcers; diabetic ulcers; tunneled, undermined wounds; trauma wounds; drainage wounds; and surgical wounds.
A large necrotizing infection in the perivulvar/perirectal space was debrided to the coccyx. The post-op wound was 15L x 8W x 9D cm. Wound V.A.C. was applied. The wound was re-debrided and irrigated, and negative pressure suction device (NPSD) was applied several times over the next three weeks, prior to the first MiroDerm Fenestrated application
Clinically proven to close hard-to-heal DFUs that had previously failed other advanced therapies1
- Single arm, multi center (9), prospective study
- All patients were non-responsive to at least two applications of one or more advanced biologic wound care product and wounds had not healed within the previous three months
- 53 patients enrolled and 38 completed per protocol over 12 weeks
In this study, MiroDerm closed DFUs that had previously failed other advanced therapies. These favorable results are consistent with a similar pilot study.2
|Treatment of Hard-to-heal Diabetic Foot Ulcers With a Hepatic-derived Wound Matrix||Robert Fridman, Payam Rafat, Carl C Van Gils, Deena Horn, Dean Vayser, C Jake Lambert, Jr||Wounds Epub 2020 June 21||
|A Pilot Study to Evaluate the Effects of Perfusion-decellularized Porcine Hepatic-derived Wound Matrix on Difficult-to-heal Diabetic Foot Ulcers||Robert Fridman and Jonathan Engelhardt||WOUNDS, October 2017||
|ITEM ID||SIZE||TOTAL cm2|
|BLM-200-02-0815||8 x 15 cm||120|
|BLM-200-02-0710||7 x 10 cm||70|
|BLM-200-02-0808||8 x 8 cm||64|
|BLM-200-02-0505||5 x 5 cm||25|
|BLM-200-02-0307||3 x 7 cm||21|
|BLM-200-02-0404||4 x 4 cm||16|
|BLM-200-02-0303||3 x 3 cm||9|
|BLM-200-02-0203||2 x 3 cm||6|
|BLM-200-02-0202||2 x 2 cm||4|
|MiroDerm Fenestrated Plus|
|BLM-200-03-0815||8 x 15 cm||120|
|BLM-200-03-0808||8 x 8 cm||64|
|BLM-200-03-0505||5 x 5 cm||25|
|BLM-200-03-0303||3 x 3 cm||9|
MiroDerm Fenestrated and MiroDerm Fenestrated Plus are processed and stored in a phosphate buffered aqueous solution, packaged in an inner sterile pouch and outer non-sterile pouch, and sterilized with electron beam irradiation. The product comes in a variety of sizes and is intended for use only by trained medical professionals who are familiar with wound procedures and techniques involving the use of a wound matrix. Federal (U.S.A.) law restricts this product to sale by or on the order of a physician.
MiroDerm Biologic Wound Matrix (Fenestrated and Fenestrated Plus) is indicated for the management of wounds, including: partial and full-thickness wounds; pressure ulcers; venous ulcers; chronic vascular ulcers; diabetic ulcers; tunneled, undermined wounds; trauma-wounds (abrasion lacerations, second-degree burns, skin tears); drainage wounds; and surgical wounds (donor sites/grafts, post-Mohs surgery, post-laser surgery, podiatric wound dehiscence).
See IFU for full prescribing information, including indications, contraindications, precautions, potential complications, and recommended application instructions.
- Fridman, R; et al. Treatment of Hard-to-heal Diabetic Foot Ulcers With a Hepatic-derived Wound Matrix. Wounds. 2020.
- Fridman, R; Engelhardt, J. A pilot study to evaluate the effects of perfusion-decellularized porcine hepatic-derived wound matrix on difficult-to-heal diabetic foot ulcers. Wounds. 2017. Vol. 29, No. 10. pp. 318-32.
SM-00155 Rev. G 08/22