Perfusion decellularized hepatic wound matrix primed for cellular integration

Designed for the management of advanced wounds

Our proprietary perfusion decellularization process results in an open collagen matrix with natural vascular pathways to assist in cellular infiltration and integration
Offered in different sizes to meet the individual patient’s clinical needs

Broad range of clinical uses

MiroDerm is a non-crosslinked acellular wound matrix derived from highly vascularized porcine liver. It is intended for the management of wounds, including partial and full-thickness wounds; pressure ulcers; chronic vascular ulcers; diabetic ulcers; tunneled, undermined wounds; trauma wounds; drainage wounds; and surgical wounds.

A large necrotizing infection in the perivulvar/perirectal space was debrided to the coccyx. The post-op wound was 15L x 8W x 9D cm. Wound V.A.C. was applied. The wound was re-debrided and irrigated, and negative pressure suction device (NPSD) was applied several times over the next three weeks, prior to the first MiroDerm Fenestrated application

Clinically proven to close hard-to-heal DFUs that had previously failed other advanced therapies¹

Single arm, multi center (9), prospective study
All patients were non-responsive to at least two applications of one or more advanced biologic wound care product and wounds had not healed within the previous three months
53 patients enrolled and 38 completed per protocol over 12 weeks

In this study, MiroDerm closed DFUs that had previously failed other advanced therapies. These favorable results are consistent with a similar pilot study.²

Clinical Data

STUDY	AUTHOR	PUBLICATION	FULL ARTICLE
Treatment of Hard-to-heal Diabetic Foot Ulcers With a Hepatic-derived Wound Matrix	Robert Fridman, Payam Rafat, Carl C Van Gils, Deena Horn, Dean Vayser, C Jake Lambert, Jr	Wounds Epub 2020 June 21	Read Here
A Pilot Study to Evaluate the Effects of Perfusion-decellularized Porcine Hepatic-derived Wound Matrix on Difficult-to-heal Diabetic Foot Ulcers	Robert Fridman and Jonathan Engelhardt	WOUNDS, October 2017	Read Here

STUDY	FULL ARTICLE
Treatment of Hard-to-heal Diabetic Foot Ulcers With a Hepatic-derived Wound Matrix	Read Here
A Pilot Study to Evaluate the Effects of Perfusion-decellularized Porcine Hepatic-derived Wound Matrix on Difficult-to-heal Diabetic Foot Ulcers	Read Here

Ordering Information

ITEM ID	SIZE	TOTAL cm²	GTIN ID
MiroDerm Fenestrated
BLM-200-02-0815	8 x 15 cm	120	00857072005156
BLM-200-02-0710	7 x 10 cm	70	00857072005149
BLM-200-02-0808	8 x 8 cm	64	00857072005132
BLM-200-02-0505	5 x 5 cm	25	00857072005125
BLM-200-02-0307	3 x 7 cm	21	00857072005118
BLM-200-02-0404	4 x 4 cm	16	00857072005170
BLM-200-02-0303	3 x 3 cm	9	00857072005163
BLM-200-02-0203	2 x 3 cm	6	00857072005293
BLM-200-02-0202	2 x 2 cm	4	00857072005309
MiroDerm Fenestrated Plus
BLM-200-03-0815	8 x 15 cm	120	00857072005262
BLM-200-03-0808	8 x 8 cm	64	00857072005248
BLM-200-03-0505	5 x 5 cm	25	00857072005231
BLM-200-03-0303	3 x 3 cm	9	00857072005200

MiroDerm Fenestrated and MiroDerm Fenestrated Plus are processed and stored in a phosphate buffered aqueous solution, packaged in an inner sterile pouch and outer non-sterile pouch, and sterilized with electron beam irradiation. The product comes in a variety of sizes and is intended for use only by trained medical professionals who are familiar with wound procedures and techniques involving the use of a wound matrix. Federal (U.S.A.) law restricts this product to sale by or on the order of a physician.

Click here for MiroDerm reimbursement information

MiroDerm Biologic Wound Matrix (Fenestrated and Fenestrated Plus) is indicated for the management of wounds, including: partial and full-thickness wounds; pressure ulcers; venous ulcers; chronic vascular ulcers; diabetic ulcers; tunneled, undermined wounds; trauma-wounds (abrasion lacerations, second-degree burns, skin tears); drainage wounds; and surgical wounds (donor sites/grafts, post-Mohs surgery, post-laser surgery, podiatric wound dehiscence).

See IFU for full prescribing information, including indications, contraindications, precautions, potential complications, and recommended application instructions.

Download IFU here.

References:

Fridman, R; et al. Treatment of Hard-to-heal Diabetic Foot Ulcers With a Hepatic-derived Wound Matrix. Wounds. 2020.
Fridman, R; Engelhardt, J. A pilot study to evaluate the effects of perfusion-decellularized porcine hepatic-derived wound matrix on difficult-to-heal diabetic foot ulcers. Wounds. 2017. Vol. 29, No. 10. pp. 318-32.